HiActi® Recombinant Human IL-12 Protein(CHO) 重组人白介素-12

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CHO表达系统免疫学细胞因子研究

Product no.90262ES Sizes4 options SourceYeasen · Official

Cat. No. 90262ES10

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90262ES10 10 μg $815.00 现货 Enquire

90262ES50 50 μg $2,445.00 现货 Enquire

90262ES80 1 mg $12,225.00 现货 Enquire

90262ES60 100 μg $4,155.00 现货 Enquire

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Overview

Specifications

Brand翌圣生物 Yeasen

Cat.No90262ES

Specification高纯度、高活性、低内毒素、高批间一致性

Origin翌圣生物科技(上海)股份有限公司

技术平台 CHO表达系统

应用方法 免疫学IL-12是细胞介导免疫反应的有效调节因子，可诱导NK细胞和T细胞产生IFN-γ 细胞因子研究研究IL-12对活化NK、CD4+和CD8+细胞生长和活性的促进作用及Th1细胞发育

适用物种种属人

检测方法 SDS-PAGE LAL法 考马斯亮蓝染色

生物特性参数 蛋白类型重组人白介素-12（细胞因子） 种属来源人 (Human) 生物活性描述Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is <0.5 ng/mL. 应用IL-12诱导NK细胞和T细胞产生IFN-γ，促进活化的NK、CD4+和CD8+细胞生长和活性，并诱导产生IFN-γ的Th1细胞发育

样本类型 重组蛋白 细胞因子

技术参数纯度≥95% by SDS-PAGE (under reducing and non-reducing conditions visualized by Coomassie staining) 内毒素水平≤0.01 EU per μg by the LAL method 分子量59 kDa (predicted) 制剂形式Lyophilized from a 0.22 μm-filtered solution containing PBS 5% mannitol and 0.01% Tween 80 pH 7.4 活性ED50 <0.5 ng/mL (measured by induction of IFN-γ secretion in NK-92 cells) 储存条件-25~-15℃保存，有效期1年；复溶后无菌条件下2~8℃保存7天；-20~-80℃保存3-6个月 表达系统CHO 标签No Tag 外观冻干粉 (Lyophilized Powder) pH7.4 Accession号P29460(p40) & P29459(p35) 表达序列Recombinant human IL-12 is composed of P40(Ile23-Ser328) and P35(Arg23-Ser219) subunits linked by GS-linker (GSGSSRGGSGSGGSGGGGSK) 复溶方法使用无菌去离子水复溶冻干的蛋白质；建议首次使用时将蛋白分装，避免反复冻融