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Product data sheet PD-40757ES
DiR Iodide (DiIC18(7)) 细胞膜深红色荧光探针 DiR Iodide (DiIC18(7)) 细胞膜深红色荧光探针
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DiR Iodide (DiIC18(7)) 细胞膜深红色荧光探针

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流式细胞术活体成像细胞荧光标记流式细胞分析体内成像
Product no.40757ES Sizes1 options SourceYeasen · Official
Cat. No. 40757ES25 现货 $938.00 促$988.00
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Cat.No Spec Price Status
40757ES25 25 mg $938.00促$988.00 现货 Enquire
Submit enquiry Price is on application; bulk sizes can be sampled on request.

Overview

Specifications

Brand翌圣生物 Yeasen
Cat.No40757ES
Specification25 mg
Origin翌圣生物科技(上海)股份有限公司
技术平台 流式细胞术 活体成像
应用方法 细胞荧光标记用于细胞膜及脂溶性结构染色 流式细胞分析用于多色流式分析 体内成像用于近红外活体成像与示踪
检测方法 近红外荧光检测
生物特性参数 染料类型亲脂性荧光染料 标记靶标细胞膜 荧光颜色深红色(近红外)
样本类型 细胞
技术参数 CAS号N/A 分子式C63H101IN2 分子量1013.4 激发/发射波长748/780 nm 推荐滤光器XF112-Omega 41009-Chroma 溶解性溶于DMSO、乙醇 储存条件-20 ºC干燥避光保存,有效期一年 运输条件冰袋运输
实验类型 细胞膜染色用于标记细胞膜 活细胞标记用于活细胞多标 流式分析用于流式细胞分析 体内示踪用于体内成像或示踪实验

FAQ

Q:这些探针染细胞,有没有细胞特异性?会不会 293 细胞不好染, MSC 好染?

A:由于这些染料是亲脂性染料,是通过插入到脂质膜中进而被激光激发观察,对于动植物细胞没有

特异性。

Q:这些探针荧光探针装载完多久后观察?

A:为减少各种可能的误差,尽量缩短探针装载后到仪器测定所用的时间(刺激时间除外)。

Q:这些探针染色细胞后,对细胞有毒性吗?

A:荧光探针类产品对活细胞都会有一定的毒性,因此建议在染色处理完成后应尽快完成检测和观察。

Q:为什么染色后发现荧光颜色较浅,应怎么操作进行改进?

A:可以尝试增加染色的时间和浓度。

Q:要看几个小时过程中活细胞的形态变化,应该怎么选?

A:通常使用亲脂性花青染料,如 DiI,DiO,DiD 或 DiR。

Q:DiRIodide(DiIC18(7))该探针在进行HPLC检测时该如何设置?

A:请使用正向色谱柱; 氯仿/甲醇~10:1。

Documents & Citations

Published citations

(部分高分文献节选)

  1. Li X, Li J, Li G, et al. Engineered immunosuppressive dendritic cells protect against cardiac remodelling. Nature. Published online April 8, 2026. doi:10.1038/s41586-026-10346-5(IF:48.5)
  2. Wu J, Song D, Li Z, et al. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis. Cell Res. 2020;30(9):794-809. doi:10.1038/s41422-020-0354-1(IF:20.507)
  3. Qin W, Xu W, Wang L, et al. Bacteria-Elicited Specific Thrombosis Utilizing Acid-Induced Cytolysin A Expression to Enable Potent Tumor Therapy. Adv Sci (Weinh). 2022;9(15):e2105086. doi:10.1002/advs.202105086(IF:16.806)
  4. Jiang YL, Wang ZX, Liu XX, et al. The Protective Effects of Osteocyte-Derived Extracellular Vesicles Against Alzheimer's Disease Diminished with Aging. Adv Sci (Weinh). 2022;9(17):e2105316. doi:10.1002/advs.202105316(IF:16.806)
  5. Chen H, Li Y, Wang Y, et al. An Engineered Bacteria-Hybrid Microrobot with the Magnetothermal Bioswitch for Remotely Collective Perception and Imaging-Guided Cancer Treatment [published online ahead of print, 2022 Mar 28]. ACS Nano. 2022;10.1021/acsnano.1c11601. doi:10.1021/acsnano.1c11601(IF:15.881)
  6. Gu Y, Lai S, Dong Y, et al. AZD9291 Resistance Reversal Activity of a pH-Sensitive Nanocarrier Dual-Loaded with Chloroquine and FGFR1 Inhibitor in NSCLC. Adv Sci (Weinh). 2020;8(2):2002922. Published 2020 Dec 4. doi:10.1002/advs.202002922(IF:15.840)
  7. Gao Y, Yang SC, Zhu MH, et al. Metal Phenolic Network-Integrated Multistage Nanosystem for Enhanced Drug Delivery to Solid Tumors. Small. 2021;17(29):e2100789. doi:10.1002/smll.202100789(IF:13.281)
  8. Guo Q, Chen C, Wu Z, et al. Engineered PD-1/TIGIT dual-activating cell-membrane nanoparticles with dexamethasone act synergistically to shape the effector T cell/Treg balance and alleviate systemic lupus erythematosus. Biomaterials. 2022;285:121517. doi:10.1016/j.biomaterials.2022.121517(IF:12.479)
  9. Liu F, Dai Z, Cheng Q, et al. LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy. Biomaterials. 2022;284:121485. doi:10.1016/j.biomaterials.2022.121485(IF:12.479)
  10. Qu F, Wang P, Zhang K, et al. Manipulation of Mitophagy by "All-in-One" nanosensitizer augments sonodynamic glioma therapy [published correction appears in Autophagy. 2022 Feb;18(2):470]. Autophagy. 2020;16(8):1413-1435. doi:10.1080/15548627.2019.1687210(IF:11.059)
  11. Li L, He D, Guo Q, et al. Exosome-liposome hybrid nanoparticle codelivery of TP and miR497 conspicuously overcomes chemoresistant ovarian cancer. J Nanobiotechnology. 2022;20(1):50. Published 2022 Jan 25. doi:10.1186/s12951-022-01264-5(IF:10.435)
  12. Dou Y, Xie J, Tan Y, Zhang M, Zhao Y, Liu X. Neurotransmitter-stimulated neuron-derived sEVs have opposite effects on amyloid β-induced neuronal damage. J Nanobiotechnology. 2021;19(1):324. Published 2021 Oct 15. doi:10.1186/s12951-021-01070-5(IF:10.435)
  13. Qi N, Zhang S, Zhou X, et al. Combined integrin αvβ3 and lactoferrin receptor targeted docetaxel liposomes enhance the brain targeting effect and anti-glioma effect. J Nanobiotechnology. 2021;19(1):446. Published 2021 Dec 23. doi:10.1186/s12951-021-01180-0(IF:10.435)
  14. Huang L, Yan W, Cai B, et al. Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner. Biomaterials. 2020;250:120021. doi:10.1016/j.biomaterials.2020.120021(IF:10.317)
  15. Chen C, Chen Y, Li M, et al. Functional decellularized fibrocartilaginous matrix graft for rotator cuff enthesis regeneration: A novel technique to avoid in-vitro loading of cells. Biomaterials. 2020;250:119996. doi:10.1016/j.biomaterials.2020.119996(IF:10.317)

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