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Q:Annexin V 和JC-1、Tunel 细胞凋亡检测的区别?
A: Annexin V 是检测细胞早期凋亡的试剂,JC-1 是检测细胞中期凋亡的试剂、Tunel 是检测细胞晚期凋亡的试剂。
Published citations
[1] Zhang M, Weng Y, Cao Z, et al. ROS-Activatable siRNA-Engineered Polyplex for NIR-Triggered Synergistic Cancer Treatment. ACS Appl Mater Interfaces. 2020;12(29):32289-32300. doi:10.1021/acsami.0c06614(IF:8.758)
[2] Duan Z , Luo Q , Gu L , et al. A co-delivery nanoplatform for a lignan-derived compound and perfluorocarbon tuning IL-25 secretion and the oxygen level in tumor microenvironments for meliorative tumor radiotherapy. Nanoscale. 2021;13(32):13681-13692. doi:10.1039/d1nr03738b(IF:7.790)
[3] Tang L, Zhang C, Lu L, et al. Melatonin Maintains Inner Blood-Retinal Barrier by Regulating Microglia via Inhibition of PI3K/Akt/Stat3/NF-κB Signaling Pathways in Experimental Diabetic Retinopathy. Front Immunol. 2022;13:831660. Published 2022 Mar 15. doi:10.3389/fimmu.2022.831660(IF:7.561)
[4] Xie H, Zhang C, Liu D, et al. Erythropoietin protects the inner blood-retinal barrier by inhibiting microglia phagocytosis via Src/Akt/cofilin signalling in experimental diabetic retinopathy. Diabetologia. 2021;64(1):211-225. doi:10.1007/s00125-020-05299-x(IF:7.518)
[5] Yue C, Yang Y, Song J, et al. Mitochondria-targeting near-infrared light-triggered thermosensitive liposomes for localized photothermal and photodynamic ablation of tumors combined with chemotherapy. Nanoscale. 2017;9(31):11103-11118. doi:10.1039/c7nr02193c(IF:7.367)
[6] Yu H, Yang X, Xiao X, et al. Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration. Aging Dis. 2021;12(6):1423-1437. Published 2021 Sep 1. doi:10.14336/AD.2021.0601(IF:6.745)
[7] Huang J, Liu Y, Chen JX, et al. Harmine is an effective therapeutic small molecule for the treatment of cardiac hypertrophy. Acta Pharmacol Sin. 2022;43(1):50-63. doi:10.1038/s41401-021-00639-y(IF:6.150)
[8] Wang X, Zhang R, Wu T, et al. Successive treatment with naltrexone induces epithelial-mesenchymal transition and facilitates the malignant biological behaviors of bladder cancer cells. Acta Biochim Biophys Sin (Shanghai). 2021;53(2):238-248. doi:10.1093/abbs/gmaa169(IF:3.848)
[9] Qu B, Han X, Zhao L, Zhang F, Gao Q. Relationship of HIF‑1α expression with apoptosis and cell cycle in bone marrow mesenchymal stem cells from patients with myelodysplastic syndrome. Mol Med Rep. 2022;26(1):239. doi:10.3892/mmr.2022.12755(IF:2.952)
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