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Elucidating Tumorigenesis Mechanisms and Assessing Immunotherapeutic Efficacy in Patient-Derived Medulloblastoma Organoid Models

International Journal of Biological Sciences · IF 11.7 · 2026 · DOI: 10.7150/ijbs.116040
关联产品: ER-Tracker Blue-White DPX, for live-cell imaging 内质网蓝色荧光探针(活细胞);CellTracker™ Red CMTPX Fluorescent Probe 细胞质红色荧光探针

In vivo CRISPR/Cas9 Screening Reveals that UBE2L3 Modulates Autophagic Flux through TSC2 Ubiquitination and Potentiates PD-1 Blockade in Triple-Negative Breast Cancer

International Journal of Biological Sciences · IF 11.7 · 2026 · DOI: 10.7150/ijbs.124937
关联产品: Annexin V-YSFluor™ 647/PI Apoptosis Detection Kit;BCA Protein Quantification Kit BCA蛋白浓度测定试剂盒(增强型)

AGPAT3 reshapes tumor cell vulnerability to IFNγ-mediated ferroptosis and enhances immunotherapy efficacy through lipid remodeling

Journal for ImmunoTherapy of Cancer · IF 11.7 · 2026 · DOI: 10.1136/jitc-2025-013305
关联产品: RPMI1640培养基(含L-谷氨酰胺;不含丙酮酸钠,HEPES,双抗);DMEM High Glucose Medium DMEM高糖培养基(含L-谷氨酰胺,丙酮酸钠110 mg/L;不含HEPES,双抗)

HDAC7-Induced Epigenetic Repression Modulates ATF3 Functional Plasticity in Colorectal Cancer Pathogenesis

International Journal of Biological Sciences · IF 11.7 · 2026 · DOI: 10.7150/ijbs.121348
关联产品: Hifair® II 1st Strand cDNA Synthesis Kit;BCA Protein Quantification Kit BCA蛋白浓度测定试剂盒(增强型);Annexin V-EGFP/PI Apoptosis Detection Kit Annexin V-EGFP/PI 细胞凋亡检测试剂盒

Biomembrane-coated Nanoparticles Targeting circHIF1α Suppress Ovarian Cancer Metastasis and Cisplatin Resistance by Mediating System Xc⁻ Inactivation via SLC7A11/SLC3A2 to Induce Ferroptosis in Cancer Stem Cells

International Journal of Biological Sciences · IF 11.7 · 2026 · DOI: 10.7150/ijbs.130412
关联产品: LysoTracker Green DND-26 溶酶体绿色荧光探针;Prussian Blue Iron Stain Kit 普鲁士蓝染色试剂盒(铁染色)

CRL4AMBRA1-mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer

International Journal of Biological Sciences · IF 11.7 · 2026 · DOI: 10.7150/ijbs.133072
关联产品: Anti-HA MagBeads Anti-HA免疫磁珠;Dual Luciferase Reporter Gene Assay Kit 双荧光素酶报告基因检测试剂盒

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