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Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1

BIOMEDICINE & PHARMACOTHERAPY · IF 6.53 · 2021 · DOI: 10.1016/j.biopha.2021.111543
关联产品: Hieff® qPCR SYBR Green Master Mix (Rox Provided Seperately);Annexin V-FITC/PI Apoptosis Detection Kit Annexin V-FITC/PI 细胞凋亡检测试剂盒

HMGCS1 drives drug-resistance in acute myeloid leukemia through endoplasmic reticulum-UPR-mitochondria axis

BIOMEDICINE & PHARMACOTHERAPY · IF 6.53 · 2021 · DOI: 10.1016/j.biopha.2021.111378
关联产品: MitoTracker® Deep Red FM 线粒体深红色荧光探针;ER-Tracker Blue-White DPX, for live-cell imaging 内质网蓝色荧光探针(活细胞);Tunicamycin from Streptomyces lysosuperficus 衣霉素

Design, synthesis and biological evaluation of novel 2-(4-(1H-indazol-6-yl)-1H-pyrazol-1-yl)acetamide derivatives as potent VEGFR-2 inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY · IF 6.51 · 2021 · DOI: 10.1016/j.ejmech.2021.113192
关联产品: Enhanced ECL Chemiluminescent Substrate Kit 增强型ECL化学发光检测试剂盒;Annexin V-FITC/PI Apoptosis Detection Kit Annexin V-FITC/PI 细胞凋亡检测试剂盒;Super ECL Detection Reagent ECL化学发光超敏显色试剂盒

Discovery of penipanoid C-inspired 2-(3,4,5-trimethoxybenzoyl)quinazolin-4(3H)-one derivatives as potential anticancer agents by inhibiting cell proliferation and inducing apoptosis in hepatocellular carcinoma cells

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY · IF 6.51 · 2021 · DOI: 10.1016/j.ejmech.2021.113671
关联产品: Cell Cycle and Apoptosis Analysis Kit 细胞周期与细胞凋亡检测试剂盒

Novel dual-mode antitumor chlorin-based derivatives as potent photosensitizers and histone deacetylase inhibitors for photodynamic therapy and chemotherapy

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY · IF 6.51 · 2021 · DOI: 10.1016/j.ejmech.2021.113363
关联产品: LysoTracker Green DND-26 溶酶体绿色荧光探针;ER-Tracker Green (BODIPY® FL Glibenclamide), for live-cell imaging 内质网绿色荧光探针(活细胞)

Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3Kδ inhibitor: Design, synthesis and biological evaluation

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY · IF 6.51 · 2021 · DOI: 10.1016/j.ejmech.2021.113661
关联产品: TUNEL Apoptosis Detection Kit (YSFluor™ 640);TUNEL Apoptosis Detection Kit (YSFluor™ 488) TUNEL细胞凋亡检测试剂盒(YSFluor™ 488);TUNEL Apoptosis Detection Kit (FITC) TUNEL细胞凋亡检测试剂盒(FITC)

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