Structure-Guided Engineering of a Cas12i Nuclease Unlocks Near-PAMless Genome Editing

Inhibition of PRMT5 triggers synthetic lethality in ARID1A-deficient endometrial cancer by…

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Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immun…

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Large-scale parallel characterization of RNA-guided nuclease activity and specificity

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Reprogramming macrophage immunometabolism via glutamine antagonism potentiates colorectal …

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Mitophagy mitigates mitochondrial DNA-induced activation of cGAS-STING in autoimmune thyro…

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Reengineered Albumin-Paclitaxel Nanoparticles Remodeling Tumor Cell Death Pathways for Pre…

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Photoactivated iridium(III) complexes drive pyroptosis–necroptosis synergy for multi-netwo…

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KMT2D loss drives adeno-to-squamous transition and sensitizes TKI-resistant lung cancer to…

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