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HEK293表达系统代谢疾病研究炎症信号研究血管生成研究

Product no.92346ES Sizes2 options SourceYeasen · Official

Cat. No. 92346ES10

现货 $1,025.00

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92346ES10 10 μg $1,025.00 现货 Enquire

92346ES50 50 μg $3,085.00 现货 Enquire

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Overview

Specifications

Brand翌圣生物 Yeasen

Cat.No92346ES

Purity> 95% as analyzed by SDS-PAGE

Specification10 μg

Origin翌圣生物科技(上海)股份有限公司

技术平台 HEK293表达系统

应用方法 代谢疾病研究研究脂联素在脂肪代谢和胰岛素敏感性中的作用 炎症信号研究研究脂联素对THF-alpha和NF-kappa-B信号通路的调控作用 血管生成研究研究脂联素在细胞生长、血管生成和组织重塑中的作用

适用物种种属人

检测方法 SDS-PAGE 凝胶凝固法 细胞增殖实验

生物特性参数 蛋白类型重组蛋白 种属来源人 生物活性描述ED50 < 2.0 μg/ml measured in a cell proliferation assay using M1 cells. 应用脂联素相关代谢、炎症及血管生成研究 功能描述脂联素是重要的脂肪因子，参与控制脂肪代谢和胰岛素敏感性；通过负调控THF-alpha表达拮抗THF-alpha；通过cAMP依赖途径抑制内皮NF-kappa-B信号传导；可形成LMW、MMW和HMW复合物，结合HBEGF、PDGFB和FGF2，在细胞生长、血管生成和组织重塑中发挥作用。

技术参数纯度> 95% as analyzed by SDS-PAGE 内毒素水平< 1.0 EU/μg of protein by gel clotting method 分子量16~17 kDa on SDS-PAGE under reducing conditions. 制剂形式Lyophilized after extensive dialysis against PBS. 储存条件-85 ~ -65℃保存，收到货之后有效期6个月。复溶后，产品在4°C下稳定2周，在-20°C下稳定3个月。避免反复冻融循环。 活性ED50 < 2.0 μg/ml measured in a cell proliferation assay using M1 cells. 表达系统HEK293 标签No Tag 复溶方法It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. 外观Lyophilized Powder 表达序列Lys101-Asn244 AccessionQ15848