Human DiI-Low Density Lipoprotein (Human DiI-LDL) 红色荧光标记人源低密度脂蛋白
勾选需要的规格可一次提交；也可以逐个询价。货号会一并带入询价单。
Q：该产品如何储存？
A：4ºC 无菌避光，收到货后可稳定保存 6 周。但不可冻存。
Q：该产品工作液可以储存多久？
A：本品的稀释工作液极不稳定，建议即配即用。
Q：该产品长期保存会出现少量沉淀，还可以使用吗？
A：这是正常现象。低速离心 1 ~2min 去除沉淀物，即得到澄清液。
Q：该产品常用缓冲液是什么？
A：含 0.02 mM EDTA 的 PBS，pH 7.4。
Q：该产品的荧光染料dil的激发光和发射光分别是多少？
A：Ex/Em是550/567 nm.
已发表文献
[1] Wang J, Zhao J, Yan C, et al. Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial. Cell Metab. 2022;34(5):667-680.e6. doi:10.1016/j.cmet.2022.03.006(IF:27.287)
[2] Heybrock S, Kanerva K, Meng Y, et al. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nat Commun. 2019;10(1):3521. Published 2019 Aug 6. doi:10.1038/s41467-019-11425-0(IF:11.878)
[3] Ma N, Fan L, Dong Y, et al. New PCSK9 inhibitor miR-552-3p reduces LDL-C via enhancing LDLR in high fat diet-fed mice. Pharmacol Res. 2021;167:105562. doi:10.1016/j.phrs.2021.105562(IF:7.658)
[4] Huang M, Zhao Z, Cao Q, et al. PAQR3 modulates blood cholesterol level by facilitating interaction between LDLR and PCSK9. Metabolism. 2019;94:88-95. doi:10.1016/j.metabol.2019.02.005(IF:6.513)
[5] Wang JQ, Lin ZC, Li LL, et al. SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1. J Biol Chem. 2021;296:100032. doi:10.1074/jbc.RA120.015420(IF:5.157)
[6] Wang D, Yang X, Chen Y, et al. Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression. J Biol Chem. 2020;295(47):15870-15882. doi:10.1074/jbc.RA120.015623(IF:4.238)
[7] Li J, Luo Y, Zhan L, et al. Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering. J Pharm Biomed Anal. 2022;211:114621. doi:10.1016/j.jpba.2022.114621(IF:3.935)
