品牌翌圣生物 Yeasen
货号 / 型号96785ES
规格高活性、高纯度、低内毒素、高稳定性
产地翌圣生物科技(上海)股份有限公司
技术平台
HEK293细胞表达系统
应用方法
免疫学研究研究先天免疫机制
肿瘤研究研究肿瘤细胞死亡机制
适用物种种属
食蟹猴
检测方法
LAL法
Bis-Tris PAGE
HPLC
生物特性参数
蛋白类型重组蛋白/靶点蛋白/抗体药物靶点蛋白
种属来源Cynomolgus (食蟹猴)
生物活性描述Innate immunity protein Tag7 (PGRP-S
PGLYRP1) can interact with the TNFα receptor
TNFR1
and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.
应用免疫调节、肿瘤细胞凋亡研究
样本类型
重组蛋白
技术参数
内毒素水平Less than 0.1 EU per μg by the LAL method.
分子量The protein has a predicted MW of 21.14 kDa. Due to glycosylation
the protein migrates to 26-30 kDa based on Bis-Tris PAGE result.
纯度>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
制剂形式Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
表达序列Recombinant Cynomolgus PGLYRP1 Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln22-His196.
标签C-His
表达系统HEK293
外观Liquid
AccessionQ18ND3
储存条件-85~-65℃保存,收到货之日起,有效期1年。建议分装蛋白为一次实验使用量,分装后,-80℃冻存。避免反复冻融。