Recombinant Cynomolgus ULBP-2 Protein,His Tag

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HEK293NK细胞生物学抗体药物靶点

Product no.96805ES Sizes3 options SourceYeasen · Official

Cat. No. 96805ES25

现货 ¥1,415.00

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96805ES25 25 μg ¥1,415.00 现货 Enquire

96805ES60 100 μg ¥5,175.00 现货 Enquire

96805ES76 500 μg ¥17,245.00 现货 Enquire

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Overview

Specifications

Brand翌圣生物 Yeasen

Cat.No96805ES

Specification高活性、高纯度、低内毒素、高稳定性

Origin翌圣生物科技(上海)股份有限公司

技术平台 HEK293

应用方法 NK细胞生物学研究ULBP-NKG2D信号通路介导的自然杀伤细胞毒性 抗体药物靶点作为靶点蛋白用于免疫治疗药物研发

适用物种种属 食蟹猴

检测方法 Bis-Tris PAGE HPLC LAL法

生物特性参数 蛋白类型ULBP-2 (NKG2D配体) 种属来源食蟹猴 (Cynomolgus) 生物活性描述ULBPs激活原代NK细胞中的多种信号通路，导致细胞因子和趋化因子产生；与NKG2D结合诱导钙动员及JAK2、STAT5、ERK和PI3K/Akt信号通路激活，介导自然杀伤细胞毒性。应用用于NK细胞功能研究及抗体药物靶点筛选 产品别称ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; RAET1L; ULBP2; ULBP-2/5/6; NKG2D ligand 2 蛋白登录号XP_001082656.3

技术参数纯度> 95% (Bis-Tris PAGE HPLC) 内毒素水平< 0.1 EU/μg (LAL法) 分子量预测23.38 kDa；由于糖基化，在Bis-Tris PAGE上迁移至25-30 kDa 制剂形式Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. 储存条件-25~-15℃保存，有效期1年；复溶后-85~-65℃保存，3个月；避免反复冻融 表达系统HEK293 标签C-His 表达序列Recombinant Cynomolgus ULBP-2 Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gly26-Ser216 复溶方法用蒸馏水溶解冻干的蛋白。如果规格为25μg或者100μg，建议复溶到0.5mg/mL的浓度。对于500μg的冻干粉，建议以1mg/mL的浓度复溶。复溶过程中请不要剧烈涡旋或者剧烈摇晃。将复溶后的蛋白溶液按照需求进行分装，储存于至-80℃，避免反复冻融。外观Lyophilized Powder