Recombinant Human CD30/TNFRSF8 Protein, His Tag

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SPRSDS-PAGE肿瘤诊断靶向治疗

Product no.94481ES Sizes4 options SourceYeasen · Official

Cat. No. 94481ES25

现货 $895.00

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94481ES25 25 μg $895.00 现货 Enquire

94481ES60 100 μg $2,845.00 现货 Enquire

94481ES76 500 μg $9,535.00 现货 Enquire

94481ES80 1 mg $18,555.00 现货 Enquire

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Overview

Specifications

Brand翌圣生物 Yeasen

Cat.No94481ES

Specification高纯度、高活性、低内毒素、高批间一致性

Origin翌圣生物科技(上海)股份有限公司

技术平台 SPR SDS-PAGE

应用方法 肿瘤诊断CD30是ALCL和cHL的诊断生物标志物 靶向治疗抗体药物偶联物靶向治疗

适用物种种属人

检测方法 LAL法 SPR法 SDS-PAGE法

生物特性参数 蛋白类型肿瘤坏死因子受体家族蛋白 种属来源人 生物活性描述CD30 regulates proliferation/apoptosis and antibody responses; expressed by activated T cells and B cells; specifically binds CD30 Ligand with affinity constant 11.5 nM (SPR). 应用用于ALCL和cHL的诊断生物标志物，以及抗体药物偶联物靶向治疗 别称TNFRSF8 CD30 D1S166E Ki-1

技术参数纯度> 95% as determined by SDS-PAGE. 内毒素水平< 1.0 EU per μg by the LAL method. 分子量Predicted MW 39 kDa; migrates as 40-50 kDa under reducing condition (SDS-PAGE) due to glycosylation. 制剂形式Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). 储存条件-25 ~ -15℃保存，收到货之后有效期1年。复溶后，无菌条件下，-85 ~ -65℃保存，3个月有效期。 表达系统HEK293 标签C-His 蛋白登录号P28908-1 表达序列Phe 19 - Lys 379 外观Lyophilized Powder 复溶方法开盖之前，先离心。使用无菌水复溶冻干的蛋白质，复溶浓度超过100 μg/mL。建议首次使用时将蛋白分装为每次实验用量，避免反复冻融。 活性SPR测定：Human CD30 Ligand (mouse Fc tag) captured on CM5 chip via Anti-mouse IgG Fc antibodies surface can bind Human CD30 His Tag with an affinity constant of 11.5 nM (Biacore 8K).