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Product data sheet PD-40112ES
Insulin human recombinant 重组人胰岛素 Insulin human recombinant 重组人胰岛素
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Insulin human recombinant 重组人胰岛素

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动物细胞培养
Product no.40112ES Sizes4 options SourceYeasen · Official
Cat. No. 40112ES25
现货 $348.00 促$387.00
Qty 1
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Specifications & Enquiry

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Cat.No Spec Price Status
40112ES25 25 mg $348.00促$387.00 现货 Enquire
40112ES60 100 mg $1,198.00促$1,327.00 现货 Enquire
40112ES76 500 mg $5,028.00促$5,587.00 现货 Enquire
40112ES80 1 g $8,518.00促$9,457.00 现货 Enquire
Submit enquiry Price is on application; bulk sizes can be sampled on request.

Overview

Specifications

Brand翌圣生物 Yeasen
Cat.No40112ES
Specification高纯度、高活性、低内毒素、高批间一致性
Origin翌圣生物科技(上海)股份有限公司
应用方法 动物细胞培养辅助成分
适用物种种属 人
生物特性参数 蛋白类型重组蛋白 种属来源人 生物活性≥ 15 U/mg 表达序列Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn)-(Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr) [Disulfide bonds Cys6/Cys11 in first branch 7 -7 between branches 20 -19 between branches
技术参数 内毒素水平<10 EU/mg 分子量5808 Da 纯度95%-105% 活性≥ 15 U/mg 制剂形式冻干粉 储存条件-25~-15℃保存 表达系统E.coli 标签No Tag 外观Lyophilized Powder 复溶方法重组人胰岛素以粉末状态供应,一般用稀盐酸溶液(10mM)溶解制成每1ml中含1~2mg的储备液,然后除菌过滤,滤液分装后可在-20℃条件下保存6个月。应避免反复冻融。 宿主残留蛋白< 10 ng/mg
实验类型 细胞培养辅助成分

FAQ

Q:能否做活体动物实验?能否观察胰岛素耐受量?

A:不能做活体实验,人的细胞可以观察胰岛素耐受。

Q:这个有配套的缓冲液吗?

A:没有缓冲液,按照说明书上用稀醋酸或者稀盐酸配置成母液就可以了。

Q:这个做脂肪细胞诱导可以吗?

A:文献中是有以胰岛素诱导脂肪细胞的,不过咱的产品没有客户验证过。这个和胰岛素作用是一样的,理论上是可以的,可以让客户尝试一下。

Documents & Citations

Published citations

[1] Chen S, Zhu G, Yang Y, et al. Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression. Nat Cell Biol. 2021;23(1):87-98. doi:10.1038/s41556-020-00613-6(IF:28.824)

[2] Niu B, Liu J, Lv B, et al. Interplay between transforming growth factor-β and Nur77 in dual regulations of inhibitor of differentiation 1 for colonic tumorigenesis. Nat Commun. 2021;12(1):2809. Published 2021 May 14. doi:10.1038/s41467-021-23048-5(IF:14.919)

[3] Li S, Han S, Zhang Q, et al. FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion. Nat Commun. 2022;13(1):3486. Published 2022 Jun 17. doi:10.1038/s41467-022-31187-6(IF:14.919)

[4] Li SL, Yang QQ, Liu XY, et al. Zn-doped Cu
2S quantum dots as new high-efficiency inhibitors against human insulin fibrillation based on specific electrostatic interaction with oligomers. Int J Biol Macromol. 2021;179:161-169. doi:10.1016/j.ijbiomac.2021.03.012(IF:6.953)

[5] Usman M, Li Y, Ke Y, et al. Trappc9 Deficiency Impairs the Plasticity of Stem Cells. Int J Mol Sci. 2022;23(9):4900. Published 2022 Apr 28. doi:10.3390/ijms23094900(IF:5.924)

[6] Yang M, Zhang M, Liu Q, et al. 18β-Glycyrrhetinic acid acts through hepatocyte nuclear factor 4 alpha to modulate lipid and carbohydrate metabolism. Pharmacol Res. 2020;157:104840. doi:10.1016/j.phrs.2020.104840(IF:5.893)

[7] Wang BB, Wang YY, Zhang XY, et al. Bifunctional carbon dots for cell imaging and inhibition of human insulin fibrillation in the whole aggregation process. Int J Biol Macromol. 2020;147:453-462. doi:10.1016/j.ijbiomac.2019.12.267(IF:5.162)

[8] Yang QQ , Jin JC , Xu ZQ , et al. Active site-targeted carbon dots for the inhibition of human insulin fibrillation. J Mater Chem B. 2017;5(10):2010-2018. doi:10.1039/c6tb02823c(IF:4.543)

[9] Zhou Z, Liu F, Wang L, et al. Inflammation has synergistic effect with nicotine in periodontitis by up-regulating the expression of α7 nAChR via phosphorylated GSK-3β. J Cell Mol Med. 2020;24(4):2663-2676. doi:10.1111/jcmm.14986(IF:4.486)

[10] Bi Y, Huang W, Yuan L, et al. HOXA10 improves endometrial receptivity by upregulating E-cadherin†. Biol Reprod. 2022;106(5):992-999. doi:10.1093/biolre/ioac007(IF:4.285)

[11] Shi H, Li XY, Chen Y, et al. Quercetin Induces Apoptosis via Downregulation of Vascular Endothelial Growth Factor/Akt Signaling Pathway in Acute Myeloid Leukemia Cells [published correction appears in Front Pharmacol. 2021 Feb 08;11:640750]. Front Pharmacol. 2020;11:534171. Published 2020 Dec 10. doi:10.3389/fphar.2020.534171(IF:4.225)

[12] Zou Y, Zhao Y, Xiao Z, et al. Comparison of Regenerative Effects of Transplanting Three-Dimensional Longitudinal Scaffold Loaded-Human Mesenchymal Stem Cells and Human Neural Stem Cells on Spinal Cord Completely Transected Rats. ACS Biomater Sci Eng. 2020;6(3):1671-1680. doi:10.1021/acsbiomaterials.9b01790(IF:4.152)

[13] Wang J, Han L, Chen J, Xie Y, Jiang H, Zhu J. Reduction of non-specific toxicity of immunotoxin by intein mediated reconstitution on target cells. Int Immunopharmacol. 2019;66:288-295. doi:10.1016/j.intimp.2018.11.039(IF:3.118)

[14] Chen JX, Li HY, Li TT, et al. Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes. BMC Complement Med Ther. 2020;20(1):22. Published 2020 Jan 29. doi:10.1186/s12906-019-2802-3(IF:2.838)

[15] Li D, Wei X, Ma M, et al. FFJ-3 inhibits PKM2 protein expression via the PI3K/Akt signaling pathway and activates the mitochondrial apoptosis signaling pathway in human cancer cells. Oncol Lett. 2017;13(4):2607-2614. doi:10.3892/ol.2017.5761(IF:1.390)

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