Ceturegel® Matrix High Concentration，LDEV-Free 基质胶
勾选需要的规格可一次提交；也可以逐个询价。货号会一并带入询价单。
Q：40187，40188，40189均是高浓度基质胶，化冻时间是多久？
A：把基质胶放入冰冰盒中，放入4度冰箱化冻3-4天左右，化冻期间可以摇晃混匀。
Q：40187，40188，40189应用方向？
A：主要应用于体内成瘤实验
Q：拿到的基质有色差的变化（淡黄色到深红色）是什么原因？
A：对于含酚红的基质胶主要原因是由于酚红和碳酸氢盐与CO2作用引起的，但与5％CO2平衡后色差即会减少。冻融后，轻轻摇晃试剂瓶使基质胶分散均匀。
Q：基质胶的操作要注意哪些事项？
A：所有操作需在无菌环境下进行，所涉及到到物品应预冷后进行操作。
Q：如融化后出现凝胶状或流动性不佳该如何处理?
A：如遇4℃冰上过夜解冻后基质胶未能呈现匀浆状（例如出现果冻状或半凝固状态，这是因高浓度基质胶特性所致），未呈现出较好流动性，同时枪头难以吸取，可使用预冷的DMEM培养基或预冷的PBS缓冲液进行稀释，另外可将枪头剪去前端一小段以助于吸取。
已发表文献
[1] Jun, J., Shaojie, L., Chao, X., et al. (2025). LHX2 rewires the metabolic and epigenetic landscape to drive tumor progression in prostate cancer. Cancer Research, *85*(23), 4751-4768. doi: 10.1158/0008-5472 (IF:16.6)
[2] Ren, W., Zheng, P., Zhou, Z., et al. (2025). Immunoglobulin-directed phase separation for cell-specific modulation of receptor signaling. Journal of the American Chemical Society, *147*(38), 34620-34631. doi: 10.1021/jacs.5c09699 (IF:15.7)
[3] Zhao, S., Liu, X., Luo, R., et al. (2025). USP38 functions as an oncoprotein by downregulating the p53 pathway through deubiquitination and stabilization of MDM2. Cell Death & Differentiation, *32*, 1128-1141. doi: 10.1038/s41418-025-01462-2 (IF:15.4)
[4] Liu, Y., Liu, F., Li, C., Zhang, T., Han, T., Dai, Y., Huang, N., Tang, H., Wang, X., Lin, S., Xue, L., & Wu, Z. B. (2025). TRIM21-mediated ubiquitination and phosphorylation of ERK1/2 promotes cell proliferation and drug resistance in pituitary adenomas. Neuro-Oncology, *27*(3), 727-742. doi: 10.1093/neuonc/noaeXXX (IF:13.4)
[5] Hu, L., Ma, X., Cai, X., et al. (2026). The mitochondrial translocation of phosphorylated EZH2 promotes PARP inhibitor resistance in BRCA1-deficient epithelial ovarian cancer. Cell Discovery, *12*, 17. doi: 10.1038/s41421-026-00880-x (IF:13)
[6] Xiao, F., Zhu, H., Xiong, Y., Guo, Y., Zhang, Z., Zeng, J., Xiao, Y., Liao, B., Shang, X., Zhao, S., Hu, G., Huang, K., & Guo, H. (2024). Positive feedback loop of c-myc/XTP6/NDH2/NF-κB to promote malignant progression in glioblastoma. Journal of Experimental & Clinical Cancer Research, *43*(1), 187. doi: 10.1186/s13046-024-03109-5 (IF:11.4)
[7] Zhou, X., Wang, J., Lu, M., Fang, L., Zhao, J., & Li, D. (2025). Leucine-rich repeat-containing 56 promotes breast cancer progression via modulation of the RhoA/ROCKs signaling axis. Molecular Biomedicine, *6*(1), 31. doi: 10.1186/s43556-025-00271-w (IF:10.1)
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